Rezolute is a late-stage rare disease company focused on significantly improving outcomes for individuals with hypoglycemia caused by hyperinsulinism (HI). Our antibody therapy, RZ358 (ersodetug), is designed to treat all forms of HI and has shown substantial benefit in clinical trials and real-world use for the treatment of congenital hyperinsulinism (cHI) and tumor hyperinsulinism (tHI).

The Senior Medical Science Liaison (Sr.MSL) will join a newly developed Medical Affairs Department. Sr.MSLs are responsible for developing and enhancing professional relationships with medical thought leaders within the metabolic and oncologic space. MSLs provide medical information through scientific exchange, and clinical/scientific support for Rezolute and the Medical Affairs department. This is a work position requires professionals with established personal and scientific credibility to interact with global thought leaders and academic centers of excellence.

Essential Functions

KOL Development and Field Engagement:

Identify and develop peer-to-peer relationships with key opinion leaders (KOLs) and healthcare providers within relevant Metabolic and Oncology therapeutic areas
Identify new, up and coming thought leaders within target therapeutic areas
Develop and execute projects and program material in alignment with evolving launch readiness plans
Identify and communicate key clinical and research issues and insights from KOLs to appropriate departments
Participate in medical education for healthcare professionals (HCPs) through virtual/on-site presentations at healthcare institutions, investigator meetings, national/international conferences, advisory boards, or regional meetings
Provide scientific support for additional activities such as medical congress staffing, advisory boards, and internal and external training initiatives

Positions self as Scientific Expert

Maintains an up to date and high-level knowledge of the therapy area, Rezolute products, new and emerging areas of research, therapeutic issues and trends, and competitive landscape.
Establishes reputation as a trustworthy and knowledgeable source of scientific and medical information for the healthcare community.
Supports development of Rezolute positioning as the scientific authority in Metabolism & Oncology therapeutic space. Attends appropriate scientific congresses to stay abreast of developments and to support International, National, Regional and local KOL activities and Rezolute interests.
Acquires a broad understanding of local, national and international protocols and standards of clinical practice and trends in disease management.
Provide clinical presentations and information in response to unsolicited questions (as appropriate) in academic, community, and healthcare provider settings in both group and one-on-one situations
Communicates emerging data and the clinical experience with our products through scientific exchange and peer-to-peer interactions discussing benefits and risks in an objective manner.
Provide support for data generation activities (company-sponsored studies, collaboration studies, ISTs and Rezolute’s Expanded Access Program)
Provide scientific support for additional activities such as medical congress staffing, advisory boards, and sales training initiatives

Medical Affairs Planning and Plan Execution

Contributes to the development of the launch readiness plans and provides input into strategies and tactics.
Where needed, manages relevant budget to enable execution of Medical Affairs tactics as part of the wider launch readiness team.
Works in a collaborative manner with cross-functional colleagues to meet defined strategic imperatives and critical success factors.
Interacts with HCPs as a scientific resource to support activities aligned with launch readiness plans including advisory boards, speaker development, publication plans and clinical trials, as appropriate.

Evidence Generation and Life Cycle Management: Strategic development and execution of data generation plans to support pipeline assets.

Collaborate cross-functionally with Clinical Development, Medical Affairs, Regulatory, and HEOR teams to align data strategies.
Identify, assess, and prioritize data gaps across the product lifecycle in alignment with clinical, medical, and future commercial objectives.
Facilitate advisory boards and expert consultations to validate data gaps and ensure scientific and clinical relevance.
Help in the development of key processes/SOPs that delineate the IIST/RWE process from proposal and protocol to contracting and publication.
Leverage KOL insights, congress findings, and emerging literature to refine evidence generation strategies.
Align data activities with regulatory submission requirements, payer evidence needs, and competitive differentiation strategies.
Monitor competitive landscape and scientific trends to proactively adjust product strategies and sustain market differentiation.

Responsible for maintaining Company standards and values

Consistently acts to enhance Rezolute’s image as an advocate of medical advancement by using knowledge of product, disease state and pipeline products to engage healthcare providers in meaningful scientific exchange of information.
Document and forward reports of adverse events and product complaints according to Rezolute's policy to ensure safe and effective use of Rezolute’s products.
Adheres to the relevant international, national and local Codes of Practice.
Behaves ethically and with integrity at all times.
Acts as an ambassador for Rezolute following company mission and values.
Keeps own written development plan and implements.
Prepares timely reporting according to the company needs.

Required Knowledge, Skills, and Abilities

Ability to research, critically analyze and communicate complex scientific/medical information and data.
Clear and concise communication and presentation skills.
Excellent planning and organization skills, with high-level attention to detail and accuracy.
Strong strategic mindset.
Highly self-motivated and ability to work autonomously.
Ability to learn quickly, be flexible and results-focused in a rapidly changing environment.
Demonstrated skills in inter-personal relationship building, networking, collaboration and teamwork.
Strong capabilities working with Microsoft suite of products and other digital platforms and tools are required
Excellent command of spoken and written English.
Ability and willingness to travel. Driving may be required.
Knowledge of healthcare environment and external experts in academia and medical community.
Demonstrated ability to develop trust and relationships with opinion leaders in disease states of interest.
Understanding of regulatory requirements for field-based personnel
Experience as a Medical Science Liaison with a strong track record of success is strongly preferred

Required Education and Licenses

Advanced medical, clinical, nursing or similar degree (such as MD, PhD, PharmD, NP, PA or equivalent)
A minimum of 5 years' experience as a MSL or comparable industry or clinical role is required, with a minimum of 2 years’ experience in rare disease.
This position will require field activities, and applicants must be willing to travel 60-75% time
Valid driver's license and live within 60 miles of an airport services by at least one major airline.

Description of Physical Demands

Frequent travel (domestic and international) with potential extended time away from home.
Frequently operating a computer, printer, telephone and other similar office machinery.
Responsibilities may require a work schedule that may include working outside of "normal" work hours, in order to meet business demands.
Frequent public contact requiring appropriate business apparel.

Preferred Experience, Special Skills and Knowledge - We are looking for a candidate that has:

Strong leadership skills and ability to effectively communicate up, down and across the organization
Ability to effectively prioritize and deliver high-quality results on tight timelines
Excellent written, verbal communication and presentation skills
Outstanding problem-solving skills including the ability to devise and implement practical solutions to resolve complex issues
Act with HONOR: Honesty, Open with Direct Communication, Nimbleness, Open-minded, Respect

Rezolute (RZLT) currently anticipates the base salary for the Senior Medical Science Liaison role could range from $170,000 to $220,000 and will depend, in part, on the successful candidate’s geographical location and their qualifications for the role, including education and experience. This position will also be eligible for an annual performance bonus in accordance with the terms of the applicable plan (depending, in part, on company and individual performance and at the Company’s discretion on an individual basis). The compensation described above is subject to change and could be higher or lower than the range described based on current market survey data and the qualifications, education, experience and geographical location of the selected candidate.

Qualifying employees are eligible to participate in benefit programs such as:

· Health Insurance (Medical / Dental / Vision)

· Disability, Life & Long-Term Care Insurance

· Holiday Pay

· Tracking Free Vacation Program

· 401(k) Plan Match

· Educational Assistance Benefit

· Fitness Center Reimbursement

We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Rezolute, Inc.

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Senior Medical Science Liaison