Mirador is a next-generation precision medicine company focused on immunology and inflammation. The company’s Mirador360TM precision development engine leverages the latest advances in human genetics and cutting-edge data science to rapidly advance new precision medicines for patients living with chronic immune-mediated inflammatory and fibrotic diseases. Launched in 2024, Mirador has raised over $400 million from leading life sciences investors and is based in San Diego, CA.
Summary
We are seeking a highly motivated hands-on physician leader to serve as Executive Director, Clinical Development who will lead a portfolio of the company’s clinical studies for current and future indications. This position will play a key role in driving the execution of studies, protocol concept, design, and conduct, to final report including interpretation of clinical data, and preparation of documents for filing with regulatory agencies.
This position will work with key stakeholders on the development of clinical protocols to support the company’s product strategy, data collection and management, and final reports development in compliance with appropriate standard operating procedures, and regulatory and medical standards. This position interacts with various groups within the company and externally to the business to ensure alignment and oversee clinical research activities.
Responsibilities
- Provide clinical leadership of trial execution from first-in-human through registrational studies.
- Provide clinical leadership in the conduct of clinical activities including recruitment, data review, analysis, and reporting that conform to the highest ethical, safety and quality standards and in compliance with GCP and regulatory standards.
- Oversee medical monitoring for and responding to safety events. Provides medical expertise ensuring the safety of the products and patients, including SAE evaluation and reporting.
- Attend and present at investigator meetings and site initiation visits as applicable.
- Provide clinical leadership in the preparation of clinical study reports, annual reports and other safety reports, health authority pre-meeting packages, investigator brochures and other periodic clinical reports.
- Collaborating with cross-functional groups to provide input in publication strategy including active participation in authoring, preparation, and review of manuscripts, conference abstracts and presentations, and other external presentations of clinical data.
- Remain current on the therapeutic landscape in the relevant therapeutic areas through review of the scientific literature, interactions with key opinion leaders and other external experts, and attendance at relevant scientific meetings, in order to provide input and guidance for the strategic direction of the company.
- Partner with Medical Affairs on the overall strategy for target product profiles, clinical trial design, and ensuring dissemination of medically accurate information related to the company’s product candidates.
Experience and Qualifications
- MD degree is required. Board Certification or Board Eligibility preferred.
- 5 years or more of experience in pharmaceutical industry clinical drug development, including protocol development; study initiation and follow-up; IRB/EC submissions and interactions; review of clinical study data listings; review and/or preparation of clinical study reports.
- The candidate should have experience with U.S. and European Health Authority interactions and have experience with submissions of clinical regulatory documents.
- Experience working across broad disease areas with an aptitude for learning equally desired.
- Experience with and implementation of practices and initiatives to ensure timelines and budgets are met with exceptional execution.
Skills and Abilities
- Strong ability to build and maintain excellent interpersonal relationships, both within and outside the company, at all levels, and work within, lead and motivate a cross-functional matrixed team.
- Self-motivated; engaged, hands-on, entrepreneurial style with a sense of urgency, a bias toward action, and flexibly contribute simultaneously in multiple facets of drug development; willingness to learn new therapeutic areas.
- Analytical and problem-solving skills; risk identification and management; creative and innovative thinking.
- The requisite scientific acumen and communication skills to influence and collaborate with key scientific, regulatory, and business leaders.
- Sound strategic, clinical, technical, operational, and ethical judgment with uncompromising integrity.
- Ability to travel 20-30%.
The expected base pay range for this position is $275,000 - $350,000 plus bonus, equity, and comprehensive benefits. The base pay range reflects the target range for this position, but individual pay will be determined by additional factors such as job-related skills, experience and relevant education or training. This range may be modified in the future.
#LI-remote
Working at Mirador Therapeutics | Great Place To Work®
All qualified applicants are considered for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity, national origin, disability, veteran status or other protected class.
Read our Job Applicant Privacy Policy