Medical Director

Codon Partners • Full-time • Remote (United States) • 10h ago

Medical Director - Gene Therapy

Codon Partners is supporting a confidential search for a Medical Director to join the gene therapy group at a biopharmaceutical company. The Medical Director will provide medical leadership for clinical development programs, helping design studies, overseeing their medical conduct, and interpreting the results that inform development decisions.

This role combines clinical strategy with hands-on study oversight. You’ll work with Clinical Operations, Safety, Biostatistics, Translational Medicine, and Regulatory Affairs to design studies that are clinically meaningful and practical for patients, caregivers, and investigators.

Key responsibilities

Contribute to clinical development plans and lead the medical aspects of study design, including patient selection, endpoint strategy, and safety monitoring.
Provide medical oversight for assigned trials. Serve as a point of contact for investigators and study teams on eligibility, protocol interpretation, and emerging clinical issues.
Review safety and efficacy data with Safety and Biostatistics. Identify trends, assess their clinical significance, and recommend actions to study and program teams.
Lead or contribute to clinical protocols, investigator brochures, clinical study reports, and the clinical sections of regulatory submissions and briefing materials.
Support health authority interactions and advise on long-term follow-up, including how to assess durability of response and monitor for delayed adverse events.
Engage investigators, clinical experts, and patient advocacy groups to bring patient and site perspectives into study design and execution.

What we’re looking for

MD, DO, or equivalent medical degree, with clinical development experience in biotech or pharma.
Experience designing or overseeing interventional clinical trials, including medical monitoring, safety review, and interpretation of clinical data.
Direct clinical development experience in gene therapy is strongly preferred. Experience in rare disease, cell therapy, or another advanced therapy is also relevant.
Ability to turn emerging clinical data into clear recommendations and communicate the rationale to cross-functional teams and senior leadership.
Experience contributing to regulatory submissions or health authority meetings is preferred.

If you would be interested in finding out more, Easy Apply below to be considered or email LinkedInApplications@Codon-Partners.com with your Resume and the role you are applying for in the subject header.